In Alzheimer’s disease, glutamate excitotoxicity which can damage neurons through chronic activation is exacerbated by deficiency of ABCA7, the second strongest genetic risk factor for the disease. The findings highlight ABCA7 and glutamate–GABA signaling as potential therapeutic targets.

· · 来源:tutorial门户

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关于作者

胡波,资深行业分析师,长期关注行业前沿动态,擅长深度报道与趋势研判。

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